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Is CBD safe for animals? What about THC?

CBD (Cannabidiol) is a Cannabis sativa derivative. Unlike another cannabinoid THC (Tetrahydrocannabinol), CBD has no psychoactive impact on the human or animal body and does not substantially influence executive brain function. However, this naturally present chemical compound promotes stress relief and relaxation in the brain and body. For this purpose, it is used in oils and edibles.  

CBD and THC share the same chemical makeup: 21 atoms in carbon, 30 atoms in hydrogen, and two atoms in oxygen. But there is a slight difference in the arrangement of the atoms, which decides the impact on the brain.  

There are two types of plants that can contain CBD: marijuana and hemp. Hemp plants have less than 0.3% THC, which is why they are the most commonly used to make CBD products.  

Why does CBD oil work for animals?  

The Endocannabinoid System (ECS) developed 600 million years ago, is present in all beings with a spinal column. The mechanism was identified in the 1990s and was previously believed to be active primarily in the brain and nerves. In 2008, scientists from the Department of Behavioral and Brain Sciences, Indiana University, Bloomington identified cannabinoid receptors in the human body, including our immune cells, fat tissue, hair, liver, pancreas, skeletal muscle, lungs, pulse, blood vessels, and gastrointestinal tract.  

Endocannabinoids are considered to this day as one of the most potent signaling molecules. The ECS induces homeostasis within the body because it includes pain, memory, mood, appetite, stress, metabolism, sleep, digestive, and reproductive functions in a wide variety of processes. This causes various illnesses and diseases when the organ is impaired or damaged — for example, anxiety, fatigue, depression, diarrhea, asthma, and cancer. CBD and THC have a close chemical composition to your endocannabinoids, which allows them to communicate with the ECS.  

How does it work for animals?  

According to some studies, the ECS is found in animals other than humans, including such obscure things as parasitic organisms and flatworms. The University of Pisa surveyed pets in 2012. The study concluded cannabinoid receptors of two forms are active in both healthy dogs’ skin and those with atopic dermatitis.   

The ECS has three essential elements, independently of the following species:  

Metabolic enzymes FAAH (Fatty Acid Amide Hydrolase) and MAGL (Monoacylglycerol Lipase) have two purposes: to stimulate and break down the endocannabinoid synthesis until it has fulfilled its function. The structure of ECS is distinct from that of neurotransmission and hormonal systems. This activates enzymes quickly and prevents cannabinoid activity. Neurotransmitters and hormones will also stay activated and be processed inside the body.  

Cannabinoid receptors reside in cell membranes that extend all over the body. We may equate them to a vehicle ignition that affects a wide variety of body functions: the sense of pain, immune system, mood, sleep, and neurogenesis. We are conscious of two receptor types: CB1 and CB2. Similar to the central nervous system, CB1 receptors are located in the brain and spinal cord. CB2 receptors are located in peripheral tissues that influence inflammatory pathways, immune systems, which digestive systems in a significant proportion.  

Endocannabinoids are fat-like molecules that our bodies create, which bind with and trigger cannabinoid receptors. Endocannabinoids are very similar to phytocannabinoids, which are the cannabinoids found in plants.  

Unfortunately, a device as complex as the ECS will malfunction, contributing to a condition known as Clinical Endocannabinoid Deficiency (CECD). This disorder leads to illness development and other dysfunctions, including migraines, irritable bowel syndrome, and fibromyalgia. Dysfunction with the ECS often creates ambiguity at a molecular stage. As metabolic enzymes refuse to release or release inappropriately, endocannabinoids begin attacking abnormal cells or ineffectively deactivating them.  

We may add plant-derived cannabinoids (phytocannabinoids) in this situation, and preserve homeostasis. Phytocannabinoids are commonly derived from Cannabis sativa and are made of the following:  

  • CBD (cannabidiol)  
  • THC (tetrahydrocannabinol)  
  • CBC (cannabichromene 
  • CBL (cannabicyclol 
  • CBN (cannabinol)  

    THC vs. CBD:  

    The most common of those are THC and CBD. Given because of their different molecular builds, these two cannabinoids interact with the ECS a little bit differently from each other.  

    THC connects in the brain with CB1 receptors that create a strong or euphoria-like feeling. Some adverse effects include elevated heart rate, difficulty with breathing, swollen eyes, sore throat, poor reflexes, and lack of memory. High levels of THC may induce adverse psychological effects in the long term.  

    CBD is deemed healthy for the care in animals since it does not bind to CB1 receptors and cannot function on the brain. Hemp-derived CBD oil is ingested into the bloodstream of your pet and can help to control the physiological processes. This phytocannabinoid is generally well tolerated. WHO published work in 2017 that shows that adverse effects may arise as a consequence of CBD usage is likely to be triggered by drug-to-drug reactions with CBD and any medications that a human or animal might be taking.  

    How is CBD good in animal treatment?  

    The number of disorders that may be alleviated by getting CBD used in the care cycle is not yet conclusive. For this article, we should concentrate on the health problems that have already been studied.  


    You have probably already noticed if your pet is afraid of some toys, is upset when you leave, or hides in the house from others. If this behavior is typical, it is a strong indication of anxiety. Prior interactions cause social anxiety. For example, an object may recall being removed from a former owner or being handled cruelly. General anxiety includes situations where the origin of distress is not easily known. Symptoms may be mild and assumed to be a natural behavior. Some pet owners, for example, define their furry companion as regularly “scared,” “miserable,” or “never satisfied.” Such dogs do not display extreme symptoms of panic in particular situations, yet much of the time, they demonstrate reduced energy rates that suggest distress. When you find the persistent fear or apprehensive behaviors persist for at least six months, you need a doctor to see your pet.  


    Our pets are frequently subjected to pathogenic bacteria. A digestive response is always able to tolerate infection. If the immune system is weak, bacteria in the cat’s body find a way to multiply and propagate. Typically, the cause of bacteria is in polluted water, waste, or undercooked food. Especially among kittens and older cats, bacterial diseases are more likely, because their immune systems are not as good as adult cats in their prime period.  

    Final note:  

    Animal studies into the influence of CBD are still in its infancy. But current clinical studies and anecdotal reports from pet owners indicate that perhaps in the most serious health problems, CBD can improve care. 

    CBD Oil: Is It Safe for Animals?

    Everyone wants their pets to live a happy and healthy life. However, when their medical conditions arise and exacerbate, we are confronted with a difficult decision to make; either we put our furry friend on various expensive treatments with probable side effects or just see them suffer.   

    Fortunately, there is now a third option: inducing all-natural cannabidiol (CBD) oil for the treatment of your animals.   

    What is CBD?   

    Cannabidiol is a non-intoxicating chemical compound, extracted from a cannabis plant that interacts with the human body’s endocannabinoid system. As a result, it contributes to maintaining homeostasis in the body.  In contrast to its counterpart tetrahydrocannabinol (THC), CBD does not render the “high” sensation.  

    How is CBD given to animals?  

    There is a wide range of options of CBD pet care products; you may probably know about the humans, such as edibles (capsules and chewable treats), oils, balms, and creams. Some can be topically applied, while others can also be added to your daily diet or taken sublingually. Like humans, each CBD product has a different effect on different types of pets, especially when it comes to dogs

    How does CBD work on pets?  

    It is still uncertain; nonetheless, scientists and researchers are still conducting studies and trials in humans. For example, dogs have an endocannabinoid system; however, whether it responds in the same manner, scientists think further experiments are still required for humans.  

    Are there any medical benefits to giving your pet CBD?   

    As mentioned, the research is still underway. However, a 2018 study discovered that CBD could contribute to increased comfort and energy in dogs suffering from osteoarthritis. The next year, another study indicated CBD to help decrease the frequency of seizures in epileptic dogs. Although these studies were adequately conducted, but they were still in preliminary stages.   

    Scientists and researchers are optimistic about CBD usage for the treatment of osteoarthritis in cats and dogs, post-operative pain, and epilepsy. It will definitely take its due time before we know the full effects of CBD. Therefore, it is better to consult with your veterinarian before administering your pet with CBD

    Is CBD safe for animals?  

    CBD, in its purest form, seems to be perfectly safe to use and is well-tolerated by animals, as per the report of the World Health Organization (WHO). However, both studies on dogs mentioned above indicated a sudden rise in the liver enzyme alkaline phosphatase (ALP) while administering CBD.  

    Researchers showed concern in giving CBD to dogs who are having liver issues. Therefore, consult with a vet about your dog’s liver condition because CBD seems to be metabolized by the liver.   

    Moreover, another thing to be wary of is the quality of CBD. Since CBD is new to the market and thus, it is not well regulated, they could include components that are not even mentioned on their labels such as THC, which is highly dangerous for animals.  

    One way to prevent buying CBD with dangerous chemical ingredients is to look for a certificate of analysis or COA. The COA batch number should match the number labeled on the product’s packaging. A COA is only issued to those products that are tested independently to verify their potency, ingredients, and various other things.   

    Can You Give CBD to Horses?

    Whether your horse is suffering from arthritis pain or gastric ulcer, they must be in very much pain. Pet owners usually opt for medical options, which are expensive and come with the risk of side effects. On the other hand, a naturally occurring compound, CBD, is trending with big displays in pharmacies, supermarkets, and stores for its several potential health benefitsIt is said that the CBD compound is beneficial for both humans and animals. So, whether you are a skeptic or advocate, it’s worth giving CBD a shot for your horse’s wellness. In this article, we explain what CBD is, how it works, and its benefits for horses. So, let’s begin!  

    What Is CBD? 

    CBD is short for cannabidiol. It is one of the many active chemical compounds present in the Cannabis sativa plant known as cannabinoids. Although both marijuana and hemp plants come from the cannabis genus, both are entirely different from each other. The hemp plant contains less than 0.3% tetrahydrocannabinol (THC) and is legal in most of America. Marijuana, on the other hand, has a significant amount of THC – a compound that consists of psychoactive properties and gets you high.  

    Therefore, one must always use hemp-derived CBD for maximum benefits without experiencing any euphoric sensation or side effects. CBD offers several potential health benefits for both human beings and pets, including cats, dogs, and horses.  

    What Ithe Endocannabinoid System?  

    The Endocannabinoid System (ECS) is a signaling system present in human beings and some animals, including horses. The ECS ensures to keep the body at homeostasis by maintaining all the functions, so the body is in stable condition.  

    CBD and other cannabinoids are responsible for the activation of ECS. Both kinds of cannabinoids which are supplied to the body (exogenous) and those produced by the body (endogenous), work primarily for endocannabinoid receptors, stimulating and balancing several functions. 

    The two main cell receptors are CB1 and CB2 receptors: 

    • CB1 receptors are primarily found in the brain and central nervous system. These receptors have a significant effect on areas like memory, appetite regulation, and emotions.  
    • CB2 receptors exist in the peripheral nervous system (nerve cells outside the spinal cord and brain), gastrointestinal tract, and modulate immune cell functions. These receptors are mainly responsible for reducing inflammation.  

    The body produces cannabinoids when required and destroys them later. On the other hand, exogenous cannabinoid may help the ECS work harder to help humans and animals with the following health problems: 

    • Depression and anxiety  
    • Pain and inflammation  
    • Insulin resistance/metabolic syndrome  
    • Obesity/leptin resistance/increased appetite  
    • Digestive disturbances/colitis/ulcers  
    • Autoimmune diseases and immune deficiencies  
    • Insomnia  

        Health Benefits of CBD for Horses  

        CBD may have many positive impacts on horses, just like it might have on human beings. Primarily, CBD helps regulate the ECS and improves overall wellbeing. Following are some of the potential benefits of CBD for horses: 

        May Reduce Anxiety and Stress  

        Humans are not the only living things that suffer from stress and anxiety; some animals also face the same problem. These issues are especially problematic before transportation. human study shows that CBD may have a calming effect and may help reduce anxiety. Since animals and human beings have a similar Endocannabinoid Systems, CBD may be useful for reducing stress and anxiety in horses as well.  

        Could Help with Inflammation  

        As horses grow older, they suffer from multiple inflammatory problems, such as desmitis, arthritis, and laminitis.  

        Desmitis is the inflammation of the ligaments, laminitis is the inflammation of sensitive layers of tissues (laminae) inside the hooves in horses, and arthritis is the inflammation of joints. These disorders can be found in all horses but are common in athletic horses. Research suggests that CBD has anti-inflammatory effects, so it may help relieve pain caused by these conditions and decrease inflammation. 

        Might Treat Gastric Ulcers   

        Another common health condition in horses is gastric ulcers. This issue affects more than 80% of racehorses and over 50% of the general population. In the digestive system of horses, a high concentration of cannabinoid receptors is present, which means that CBD may have positive effects on their health.  

        Although CBD research for gastric ulcers in horses is lacking, a study on rats indicates that the CBD can decrease gastric acid secretion. As it has anti-inflammatory effects, it might even treat other digestive disorders, such as colic.  

        May Assist with Blood Flow  

        Sometimes horses have swelling in their legs, and it can happen due to several reasons. The most common cause is the fluid that has built up from the blood vessels in the legs. It is not only uncomfortable but painful as well. As  CBD may assist with blood flow throughout the body, it may also help decrease swelling of these susceptible areas.  

        Is CBD Safe for Horses to Consume?  

        One of the main selling points of CBD is its safety and purity. As the compound is naturally present and derived through CO2 extraction, it does not cause any harmful effects, unlike many pharmaceutical drugs. Still, it is important to note that the CBD might have some minor effects, such as: 

        • Drowsiness or fatigue  
        • Increased thirst  
        • Change in appetite  
        • Restlessness  
        • Unbalance blood pressure  

        These adverse effects usually take place during the initial stages of CBD consumption as the horse’s body is not familiar with the compound. It is best to begin with the lowest possible dosage and gradually increase it over time; it will help you reduce the risk of the abovementioned side effects.  

        Where to Buy CBD?  

        If you are looking for the original and high-quality CBD productsNature Blend is the platform to trust. They provide 100% natural, CO2 extracted, and clinically tested CBD products to help you and your pets cure multiple health conditions.