main logo


A black and white dog relaxing in its owner's lap.

Is CBD safe for animals? What about THC?

CBD (Cannabidiol) is a Cannabis sativa derivative. Unlike another cannabinoid THC (Tetrahydrocannabinol), CBD has no psychoactive impact on the human or animal body and does not substantially influence executive brain function. However, this naturally present chemical compound promotes stress relief and relaxation in the brain and body. For this purpose, it is used in oils and edibles.  

CBD and THC share the same chemical makeup: 21 atoms in carbon, 30 atoms in hydrogen, and two atoms in oxygen. But there is a slight difference in the arrangement of the atoms, which decides the impact on the brain.  

There are two types of plants that can contain CBD: marijuana and hemp. Hemp plants have less than 0.3% THC, which is why they are the most commonly used to make CBD products.  

Why does CBD oil work for animals?  

The Endocannabinoid System (ECS) developed 600 million years ago, is present in all beings with a spinal column. The mechanism was identified in the 1990s and was previously believed to be active primarily in the brain and nerves. In 2008, scientists from the Department of Behavioral and Brain Sciences, Indiana University, Bloomington identified cannabinoid receptors in the human body, including our immune cells, fat tissue, hair, liver, pancreas, skeletal muscle, lungs, pulse, blood vessels, and gastrointestinal tract.  

Endocannabinoids are considered to this day as one of the most potent signaling molecules. The ECS induces homeostasis within the body because it includes pain, memory, mood, appetite, stress, metabolism, sleep, digestive, and reproductive functions in a wide variety of processes. This causes various illnesses and diseases when the organ is impaired or damaged — for example, anxiety, fatigue, depression, diarrhea, asthma, and cancer. CBD and THC have a close chemical composition to your endocannabinoids, which allows them to communicate with the ECS.  

How does it work for animals?  

According to some studies, the ECS is found in animals other than humans, including such obscure things as parasitic organisms and flatworms. The University of Pisa surveyed pets in 2012. The study concluded cannabinoid receptors of two forms are active in both healthy dogs’ skin and those with atopic dermatitis.   

The ECS has three essential elements, independently of the following species:  

Metabolic enzymes FAAH (Fatty Acid Amide Hydrolase) and MAGL (Monoacylglycerol Lipase) have two purposes: to stimulate and break down the endocannabinoid synthesis until it has fulfilled its function. The structure of ECS is distinct from that of neurotransmission and hormonal systems. This activates enzymes quickly and prevents cannabinoid activity. Neurotransmitters and hormones will also stay activated and be processed inside the body.  

Cannabinoid receptors reside in cell membranes that extend all over the body. We may equate them to a vehicle ignition that affects a wide variety of body functions: the sense of pain, immune system, mood, sleep, and neurogenesis. We are conscious of two receptor types: CB1 and CB2. Similar to the central nervous system, CB1 receptors are located in the brain and spinal cord. CB2 receptors are located in peripheral tissues that influence inflammatory pathways, immune systems, which digestive systems in a significant proportion.  

Endocannabinoids are fat-like molecules that our bodies create, which bind with and trigger cannabinoid receptors. Endocannabinoids are very similar to phytocannabinoids, which are the cannabinoids found in plants.  

Unfortunately, a device as complex as the ECS will malfunction, contributing to a condition known as Clinical Endocannabinoid Deficiency (CECD). This disorder leads to illness development and other dysfunctions, including migraines, irritable bowel syndrome, and fibromyalgia. Dysfunction with the ECS often creates ambiguity at a molecular stage. As metabolic enzymes refuse to release or release inappropriately, endocannabinoids begin attacking abnormal cells or ineffectively deactivating them.  

We may add plant-derived cannabinoids (phytocannabinoids) in this situation, and preserve homeostasis. Phytocannabinoids are commonly derived from Cannabis sativa and are made of the following:  

  • CBD (cannabidiol)  
  • THC (tetrahydrocannabinol)  
  • CBC (cannabichromene 
  • CBL (cannabicyclol 
  • CBN (cannabinol)  

    THC vs. CBD:  

    The most common of those are THC and CBD. Given because of their different molecular builds, these two cannabinoids interact with the ECS a little bit differently from each other.  

    THC connects in the brain with CB1 receptors that create a strong or euphoria-like feeling. Some adverse effects include elevated heart rate, difficulty with breathing, swollen eyes, sore throat, poor reflexes, and lack of memory. High levels of THC may induce adverse psychological effects in the long term.  

    CBD is deemed healthy for the care in animals since it does not bind to CB1 receptors and cannot function on the brain. Hemp-derived CBD oil is ingested into the bloodstream of your pet and can help to control the physiological processes. This phytocannabinoid is generally well tolerated. WHO published work in 2017 that shows that adverse effects may arise as a consequence of CBD usage is likely to be triggered by drug-to-drug reactions with CBD and any medications that a human or animal might be taking.  

    How is CBD good in animal treatment?  

    The number of disorders that may be alleviated by getting CBD used in the care cycle is not yet conclusive. For this article, we should concentrate on the health problems that have already been studied.  


    You have probably already noticed if your pet is afraid of some toys, is upset when you leave, or hides in the house from others. If this behavior is typical, it is a strong indication of anxiety. Prior interactions cause social anxiety. For example, an object may recall being removed from a former owner or being handled cruelly. General anxiety includes situations where the origin of distress is not easily known. Symptoms may be mild and assumed to be a natural behavior. Some pet owners, for example, define their furry companion as regularly “scared,” “miserable,” or “never satisfied.” Such dogs do not display extreme symptoms of panic in particular situations, yet much of the time, they demonstrate reduced energy rates that suggest distress. When you find the persistent fear or apprehensive behaviors persist for at least six months, you need a doctor to see your pet.  


    Our pets are frequently subjected to pathogenic bacteria. A digestive response is always able to tolerate infection. If the immune system is weak, bacteria in the cat’s body find a way to multiply and propagate. Typically, the cause of bacteria is in polluted water, waste, or undercooked food. Especially among kittens and older cats, bacterial diseases are more likely, because their immune systems are not as good as adult cats in their prime period.  

    Final note:  

    Animal studies into the influence of CBD are still in its infancy. But current clinical studies and anecdotal reports from pet owners indicate that perhaps in the most serious health problems, CBD can improve care.